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Tirzepatide represents a dual-action approach, targeting both GLP-1 and GIP receptors to influence insulin secretion, glucagon suppression, and gastric emptying

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Keywords: citrus flavonoids, eriocitrin, GLP-1, hyperglycemia, nutraceutical, systemic inflammation INTRODUCTION Currently, type 2 diabetes (T2D) affects almost a half billion people worldwide (468 million in 2017), corresponding to 6.3% of the world population, with the majority being individuals over 50 years of age and, to a lesser extent, adolescents and young adults who already show signs of the disease